With the continuously expanding COVID-19 pandemic, increasing numbers of patients and contacts are progressively posing a global challenge. Being novel, there is so much that is yet to be known about this virus and how to manage it. This scenario is not only true for conventional medicine, but is also applicable to herbal medicine and natural products. An ideal anti-COVID-19 medication (or a combination of agents) should be safe for patients while conferring three basic therapeutic effects (and/or preventive health benefits):